Saturday, January 25, 2014

Gland

Glandular epithelium:

A)Presence or absence of ducts

 •Exocrine – ducted

 •Endocrine - ductless

B)Uni- or multicellular

C)Mode of secretion

D)  Secretion products

Gland categories :

1)  Exocrine - glands that exude secretions into a ductule system. Have two parts, acinous = secretory bulb and ductule.

2)  Endocrine - glands exuding secretions directly into body fluids, ultimately blood.

3)  Mixed - glands combining both the above characteristics (e.g. pancreas) in the same cell

Cellular composition :

1)Unicellular - single cell gland, Goblet cell;  mucous secreting.  GI tract, respiratory ducts. Secretion process alters cell and nucleus shape.

2)  Multicellular - 

  a)  intra epithelial gland - gland is entirely within a layer of epithelium. Common in pseudostratified columnar  epithelium.

 b)  extra epithelial gland - in Connective Tissue below epithelium; may   have different shapes; tubular  and  acinar


Modes of Secretion(how products leave the cell)

1)  Merocrine - secretion does not affect the well-being of the cell = sweat glands.

2)  Apocrine - small part of the cell cytoplasm is lost with the secretion; the cell is damaged   but not killed = mammary glands.

3)  Holocrine - great deal of cytoplasm is lost with the secretion; the cell dies.Sebaceous   glands.

Secretion product

1)  serous - thin, watery fluid, product of serous cells, small pink staining cuboidal cells with spherical to elliptical nuclei; salivary glands,sweat glands, pancreatic acinar

.2)  mucous - thicker, viscous secretion, product of mucous cells, large blue staining cuboidal cells with flat, elongate nuclei; GI tract, oral   cavity.

3)  mixed serous-mucous - oral cavity, salivary.

4) sebaceous - thick, lipid rich secretions of cuboidal cells in certain skin regions - face, nose, axillary and pubic regions.

Myoepithelium:

Myoepithelium - specialized squamous epithelial cells with powers of contraction;

Surround glandular acini and ducts of many glands,

Contain actin, myosin, cytotokeratin =definitely epithelial in origin, not muscle...